http://www.plosone.org/article/info:...l.pone.0012033
Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men
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Tempus speak translation (and the reason I posted it.)
15 guys (age 20-22) - no notes on if they are experienced weight trainers, couch potatoes or whatever
unilateral leg extensions -
3 different versions - 90%1RM to failure, 30%1RM to same reps as 90%1RM, 30%1RM to failure.
Result - 30%1RM to failure resulted in myofibrillar protein synthesis remained elevated (199%) above rest at 24 h. The rest didn't.
Why we care - myofibrillar is the "get stronger" version of muscle growth (as opposed to sarcoplasmic aka. fluid growth.)
Do we really care?
I don't know. If these are untrained guys then this study probably doesn't translate. Its all about newbie gains and their CNS giving out with the higher intensity.
If they are experienced resistant trained lifters -- then it might be worth looking at.